Phosphatidylglycerol (PG) phospholipid membawa caj negatif disebabkan oleh kumpulan negatif dikenakan kutub fosfat mereka, memberikan keseluruhan molekul negatif dikenakan. Bergantung kepada rantai asid lemak, biasa PG phospholipid seperti dipalmitoylphosphatidylglycerol (DPPG) dan dimyristoylphosphatidylglycerol (DMPG) menunjukkan perbezaan yang signifikan dalam fasa peralihan suhu.
NMPA CDE pendaftaran no.: F20180000838(A)
USFDA DMF no.: 032797
| Product Name | Dipalmitoyl Phosphatidylglycerole |
| Chemical Name | 1,2-Dipalmitoyl-sn-glycero-3-phosphatidylglycerol (sodium salt) |
| CAS No. | 200880-41-7 |
| NMPA CDE registration no. | F20180000838 |
| USFDA DMF No. | 032797 |
| Quality grade | Injection |
| Quality standards | Manufacturer's standard |
| Molecular Formula | C38H74O10PNa |
| Applications and examples | This product is Dipalmitoyl Phosphatidylglycerole (for injection), a fully synthetic phospholipid. It is suitable for the preparation of anionic liposomes and is a common choice of negatively charged membrane materials. It also plays a key role in improving the stability of liposomes. It has been widely used in the R&D of liposome drugs and the prescriptions of marketed products, and has also been used in some liposome projects in clinical stages, e.g., Lipoplatin. |
| Product code | S02003 |
| Package sizes | 1g, 10g |
| Storage condition | The product should be transported at -20 ± 5℃. It should be stored at -20℃ in well-closed containers, protected from light. Avoid exposure to strongly oxidizing media. It should be retested every 12 months when used and stored properly. |
Phosphatidylglycerol (PG) phospholipid digunakan secara meluas dalam penyediaan liposomes;
Zarah Lipid dengan caj negatif boleh menghalang pengagregatan zarah, dengan itu meningkatkan kestabilan formulasi;
Zarah lipid negatif dikenakan adalah lebih cenderung untuk menembusi membran sel untuk penghantaran.
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